Presented by Anthony Sorrentino, MD, Clinical Informatics Fellow at Duke University Health System and Primary Care Doctor at Duke Primary Care Riverview, this session explores the strengths and limitations of clinical registry data in research. While real-world data sources such as EHRs and medical claims are widely used, clinical registries stand out for containing detailed, manually abstracted outcomes data. Dr. Sorrentino discusses the challenges of working with registry data, including siloed storage, limited access, and complex governance. He introduces Duke’s pilot data mart, which links multiple clinical registries with EHR data to enable broader research use, and highlights design strategies, key barriers encountered, and ongoing efforts to transform registry data into a more integrated and accessible research asset. WATCH
