Housed within the School of Medicine but drawing leadership, resources, and insights from across the entire University, AI Health’s executive leadership combines clinical knowledge and quantitative insight. AI Health is led by Duke School of Medicine Vice Dean for Data Science Michael J. Pencina, PhD with Managing Director Shelley Rusincovitch, MMCi, an informaticist and technical leader, and advised by Richard Shannon, MD, the Chief Quality Officer and Chief Medical Officer for Duke Health, and Jennifer Lodge, PhD, the Vice President for Research and Innovation at Duke University. Under their guidance, AI Health is devoted to growing ethical and equitable data science and addressing the most urgent and difficult challenges in medicine and population health.